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research projects are run jointly at the Department
of Human and Clinical Genetics & the Department of Neurology of the Leiden University
Medical Center, The Netherlands, and are coordinated by prof. Dr. Rune
and Dr. Michel D. Ferrari. The main aims of our research are the
characterization of genes involved in episodic neurological disorders
(including migraine, cluster headache, epilepsy and narcolepsy) and the
functional analysis of the roles of these genes in the pathophysiology of the
diseases, using transgenic mouse model approaches. Hopefully, these studies
will result in the development of new, preferably prophylactic, ways to treat
the mentioned disorders.