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In
the last years we generated several transgenic mouse models by
introduction of 4qter genomic fragments in the mouse genome. At this
moment, a total of 17 transgenic lines are available, covering
approximately 200 kb of 4qter. These lines are currently being studied
for their phenotype and expression of the transgenes. (More
information: Tonnie Rijkers, PhD. E-mail :
rijkers@lumc.nl or Silvère van der
Maarel, Ph.D. E-mail: maarel@lumc.nl).
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