BCLC-study: A Collaborative Study of Male Breast Cancer

Coordinator Susan Neuhausen (Salt Lake City, USA)
Aim To examine variants in genes which may be associated with risk of developing male breast cancer.
Calls for For both cases and controls, approximately 10 micrograms of DNA, data on family history and a completed questionnaire is requested. Click here for more details.
Status Data collecting in progress; deadline  June 1, 1999

Purpose

To examine variants in genes which may be associated with risk of developing male breast cancer.

Study Design

The design will be a population-based case-control study. Cases are males with a diagnosis of breast cancer. Controls will be matched on year of birth, ethnicity, and geographic locale. For both cases and controls, approximately 10 micrograms of DNA, data on family history and a questionnaire is required. The questionnaire will be sent to those who have indicated to participate. For the cases, if you know the BRCA1 and BRCA2 mutation-status that would be helpful. Otherwise mutation screening can be performed by the coordinating center.

Initial genes to be examined for association study:

Participation and deadline

Please send your fax number to Susan Neuhausen if you are interested in participating in this study. She will send you the male breast cancer questionnaire. Ideally, please send samples by June 1, 1999. However, samples can be sent beyond that date as you receive them. Genotyping will be done at by Susan at the University of Utah in order to ensure consistency in allele calling. Alternatively, you can perform your own genotyping, in which case you will receive some control DNA from Susan.

Publication

As always, publications will include all contributors.

Contact

Susan Neuhausen
Genetic Epidemiology Lab
University of Utah
410 Chipeta Way, Rm. 105
Salt Lake City, UT 84108
USA
e-mail: susan@episun5.med.utah.edu
Phone: 1-801-581-6144
FAX: 1-801-581-6052


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Last updated: December 17, 1998