BCLC-study: Genotype-phenotype correlations at BRCA1 and BRCA2

Coordinator Doug Easton (Cambridge, UK) 
Aim To investigate claims existing in the literature that mutations occurring in certain regions of BRCA1 and BRCA2 are associated with a different breast:ovarian cancer ratio.
Calls for Ascertainment data on breast and ovarian cancer in families with a proven mutation in either BRCA1 or BRCA2.
Status Data acquisition closed; analysis finalized; manuscript in preparation.

May 5, 1999