DNA samples from BRCA1 carriers received to date

Mutation

no. fams referring group country sample location
185delAG 5 Narod Canada IARC
185delAG 2 Bignon France IARC
185delAG 9 Stoppa-Lyonnet France IARC
185delAG 5 Olah Hungary -
185delAG 1 Friedman India IARC
185delAG 3 Friedman Iraq IARC
185delAG 14 Abeliovich Israel IARC
185delAG 3 Friedman Morocco IARC
185delAG 4 van den Ouweland Netherlands IARC
185delAG 1 Moller Norway IARC
185delAG 2 Baiget Spain IARC
185delAG 8 Evans UK IARC
185delAG 6 Eeles UK IARC
185delAG 1 Schofield UK IARC
185delAG 3 Struewing USA IARC
185delAG 1 Badzioch USA IARC
185delAG 3 Lynch USA IARC
185delAG 2 USA USA IARC
185delAG 3 Wagner Austria Vienna
185delAG 1 Radice Italy Vienna
185delAG 2 Devilee Netherlands Vienna
185delAG 1 Ligtenberg Netherlands Vienna

TOTAL

80      
Cys61Gly 12 Olah Hungary -
Cys61Gly 1 Cipollini Italy IARC
Cys61Gly 2 USA USA IARC
Cys61Gly 1 Struewing USA IARC
Cys61Gly 1 Lynch USA IARC
Cys61Gly 6 Wagner Austria Vienna
Cys61Gly 1 Fricker France Vienna
Cys61Gly 4 Doerk Germany Vienna
Cys61Gly 1 Munic Germany Vienna
Cys61Gly 1 Heidelberg Germany Vienna
Cys61Gly 1 Borg Sweden Vienna/IARC

TOTAL

31      
IVS5-11T>G (ins 59 bp) 1 Narod Canada IARC

TOTAL

1      
1014ins/del 1 Eeles UK IARC

TOTAL

1      
1135insA 1 Bignon France IARC
1135insA 1 Garvin Italy IARC
1135insA 11 Moller Norway IARC
1135insA 2 Borg Sweden IARC
1135insA 1 Wagner Austria Vienna
1135insA 1 Radice Italy Vienna
1135insA 1 Borg Sweden Vienna

TOTAL

18      
1294del40 1 Evans UK IARC
1294del40 1 Schofield UK IARC
1294del40 1 Struewing USA IARC
1294del40 2 Narod Canada Utah

TOTAL

5      
1623del5 1 Eeles UK IARC

TOTAL

1      
1675delA 24 Moller Norway IARC
1675delA 2 Borg Sweden IARC

TOTAL

26      
1806C>T 4 USA USA IARC
1806C>T 7 Wagner Austria Vienna
1806C>T 1 Teugels Belgium Vienna
1806C>T 4 Narod Canada Vienna
1806C>T 1 Aviano Italy Vienna
1806C>T 1 Radice Italy Vienna
1806C>T 8 Borg Sweden Vienna

TOTAL

26      
2080delA 1 Schofield UK IARC
2080delA 1 Ligtenberg Netherlands Vienna

TOTAL

2      
2371delTG 1 Eeles UK IARC

TOTAL

1      
2457C>T 2 Devilee Netherlands Vienna
2457C>T 3 Ligtenberg Netherlands Vienna

TOTAL

5      
3053delT 2 USA USA IARC

TOTAL

2      
3153del4 5 Wagner Austria Vienna

TOTAL

5      
3508C>G 1 USA USA IARC

TOTAL

1      
3600del11 1 Hardouin France IARC
3600del11 1 Cipollini Italy IARC
3600del11 1 Struewing USA IARC
3600del11 3 Wagner Austria Vienna
3600del11 7 Fricker France Vienna
3600del11 1 Radice Italy Vienna

TOTAL

14      
3604delA 4 Nevanlinna Norway IARC
3604delA 4 Ligtenberg Netherlands Vienna

TOTAL

8      
4446C>T 1 Messiaen Belgium IARC
4446C>T 1 Narod Canada IARC
4446C>T 3 Hardouin France IARC

TOTAL

5      
3867G>T 1 Voglino Italy IARC
3867G>T 4 Ligtenberg Netherlands Vienna

TOTAL

5      
3875del4 1 USA USA IARC
3875del4 3 Eeles UK IARC
3875del4 1 Radice Italy Vienna

TOTAL

5      
4184del4 1 Moller Norway IARC
4184del4 1 Eeles UK IARC

TOTAL

2      
4302C>T 1 Lidereau France IARC
4302C>T 1 Wagner Austria Vienna
4302C>T 1 Stamm/Berlin Germany Vienna

TOTAL

3      
4446C>G 1 Radice Italy Vienna

TOTAL

1      
5256delG 1 USA USA IARC

TOTAL

1      
5370C>T 2 Wagner Austria Vienna
5370C>T 1 Nevanlinna Finland Vienna

TOTAL

3      
5382insC 6 Narod Canada IARC
5382insC 1 Hardouin France IARC
5382insC 1 Lidereau France IARC
5382insC 1 Bignon France IARC
5382insC 7 Stoppa-Lyonnet France IARC
5382insC 15 Olah Hungary -
5382insC 3 Abeliovich Israel IARC
5382insC 2 Cipollini Italy IARC
5382insC 4 van den Ouweland Netherlands IARC
5382insC 1 Moller Norway IARC
5382insC 1 Evans UK IARC
5382insC 3 USA USA IARC
5382insC 2 Struewing USA IARC
5382insC 4 Lynch USA IARC
5382insC 2 Badzioch USA IARC
5382insC 4 Wagner Austria Vienna
5382insC 4 Teugels Belgium Vienna
5382insC 1 Sibille Belgium Vienna
5382insC 1 Nevanlinna Finland Vienna
5382insC 1 Fricker France Vienna
5382insC 8 Doerk Germany Vienna
5382insC 4 Stamm/Berlin Germany Vienna
5382insC 2 Munic Germany Vienna
5382insC 13 Radice Italy Vienna
5382insC 2 Aviano Italy Vienna
5382insC 4 van den Ouweland Netherlands Vienna
5382insC 1 Devilee Netherlands Vienna
5382insC 1 van der Hout Netherlands Vienna
5382insC 1 Borg Sweden Vienna

TOTAL

100      
5622C>T 2 Ligtenberg Netherlands Vienna

TOTAL

2      

 

Chart BRCA1 mutations


Last Updated on 2-7-1999
By Csilla Szabo